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Mitsuho Taniguchi

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Articles

Tri-Culture System Reveals an Activation Cascade From Microglia Through Astrocytes to Neurons During Neuroinflammation

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By Hayato Kobayashi, Hiroshi Kato, Mitsuho Taniguchi
| Wiley Online Library Verified
ANOVA analysis of variance APCs astrocyte progenitor cells BPM beats per minute iPSCs induced pluripotent stem cells LPS lipopolysaccharide NF-κB nuclear factor kappa B TNF-α tumor necrosis factor-alpha 1 Introduction Microglia are immune cells in the brain, serving a vital role in defending the brain against pathogens and tissue damages. Microglia quickly detect changes in the brain environment, and they remove pathogens and cellular debris, subsequently triggering inflammation (Xu et al. 2016).
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