Mitsushi J. Ikemoto

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Efficient and specific selection of high-affinity DNA aptamers targeting μ-opioid receptor via functional extracellular vesicles

Jul 06, 2026 |

By Yuji Kamikubo, Daisuke Uta, Masanobu Kano, Takashi Sakurai, Mitsushi J. Ikemoto, Kengo Kirinoki, Mari Kiriyama, Takumi Miyajima, Hakushun Sakairi, Toshihide Tabata

| Nature

Abstract Nucleic acid aptamers are promising next-generation experimental and therapeutic drugs for uncharacterized biomolecules and intractable diseases. However, efficient aptamer selection remains challenging.

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Mitsushi J. Ikemoto

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Efficient and specific selection of high-affinity DNA aptamers targeting μ-opioid receptor via functional extracellular vesicles

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