Mogens Holst Nissen on Muck Rack

Mogens Holst Nissen

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Articles

Regulatory effects of beta-2-microglobulin on reactive oxygen species generation in polymorphonuclear cells

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By Maria Steffensen, Peter Jensen, Frederik Vilhardt, Sofie Espersen Poulsen, Ellen Magdalena Staudinger, Mogens Holst Nissen
| Nature
Abstract Beta-2-microglobulin (β2m) constitutes the invariant light chain of the major histocompatibility complex class I (MHC I) and is therefore expressed on all nucleated cells. Soluble β2m is present in biological fluids, platelets and neutrophil granules. Immune and epithelial cells can upregulate the production and secretion of β2m in response to pro-inflammatory cytokines.
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