Mohamed-Eslam F on Muck Rack

Mohamed-Eslam F

As seen in: Oxford University Press (OUP)
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Articles

Cedirogant in adults with psoriasis: a phase 2, randomized, placebo-controlled clinical trial

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By H Chih-ho, Mohamed-Eslam F
| Oxford University Press (OUP)
Dysregulated interleukin (IL)-17/IL-23 signaling contributes to psoriasis pathogenesis. Cedirogant is an inverse agonist of retinoic acid–related orphan receptor gamma thymus (RORγt), a key transcription factor responsible for IL-17 synthesis and a regulator of the T helper 17 cell lineage program. To evaluate the efficacy and safety of cedirogant to treat moderate-to-severe psoriasis.
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