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Mohammad Murwih Alidmat on Muck Rack

Mohammad Murwih Alidmat

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Articles

Green synthesis of tetrahydropyridine-3-carboxylate derivatives and evaluation of antimicrobial and antimalarial activities supported by molecular docking, POM studies, and drug-likeness analysis

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By Bhavesh Hirani, Luai Hasoun, Sevak B. Gurubaxani, Ahmad Sundookah, Sumeer Ahmed, Mohd Ali, Ajmal R. Bhat, Hamad A. Al-Lohedan, Mohammad Murwih Alidmat, Habtamu Abebe Agisho, Maria Zbancioc
| Nature Verified
Abstract A series of novel haloarene-decorated tetrahydropyridine derivatives B(1a–1f) were synthesized via a simple, environmentally benign one-pot multicomponent reaction employing ethanol as a green solvent and [Et₃NH][HSO₄] as a Brønsted acid ionic liquid catalyst. The reaction utilized methyl acetoacetate (1 mmol), substituted aromatic aldehydes (2 mmol), and substituted anilines (2 mmol) at 60 °C to afford the desired compounds.
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