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Mohammad Owais Ansari on Muck Rack

Mohammad Owais Ansari

As seen in: BioRxiv
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Articles

CaMKKβ regulates transcription factor Elf2 gene methylation to maintain endothelial junctional barrier integrity

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By Dong-Mei Wang, Juan Yang, Zarema Arbieva, Mohammad Owais Ansari
| BioRxiv
Abstract The expression of endothelial-enriched receptor tyrosine kinase Tie2 and vascular endothelial cadherin VE-cadherin in endothelial cells (EC) is essential for maintaining endothelial barrier integrity and vascular homeostasis. The Ets family of transcription factors plays a critical role in regulating the expression of Tie2 and VE-cadherin in EC. However, the transcriptional regulation of these factors remains poorly understood.
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