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Articles by Mohammad Simchi
International multisite implementation of distributed cell-free protein biomanufacturing to advance health and research equity
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Limitations in global access to research and health care capacity undermine equity, sustainability, and resilience, particularly in resource-limited settings.
High-throughput sperm DNA analysis at the single-cell and population levels
High-throughput sperm DNA analysis at the single-cell and population levels† Mohammad Simchi, a Jason Riordon, a Yihe Wang,a Christopher McCallum,a Jae Bem You, a Keith Jarvi,b Reza Nosrati *c and David Sinton *a Abstract Clinical semen quality assessment is critical to the treatment of infertility. Sperm DNA integrity testing provides critical information that can steer treatment and influence outcomes and offspring health.
Integrating machine learning and digital microfluidics for screening experimental conditions
Integrating machine learning and digital microfluidics for screening experimental conditions† Fatemeh Ahmadi, abc Mohammad Simchi, d James M. Perry, b Stephane Frenette,b Habib Benali,ab Jean-Paul Soucy, be Gassan Massarwehe and Steve C. C. Shih *abc Abstract Digital microfluidics (DMF) has the signatures of an ideal liquid handling platform – as shown through almost two decades of automated biological and chemical assays.
Integrating machine learning and digital microfluidics for screening experimental conditions
Integrating machine learning and digital microfluidics for screening experimental conditions† Fatemeh Ahmadi, abc Mohammad Simchi, d James M. Perry, b Stephane Frenette,b Habib Benali,ab Jean-Paul Soucy, be Gassan Massarwehe and Steve C. C. Shih *abc Abstract Digital microfluidics (DMF) has the signatures of an ideal liquid handling platform – as shown through almost two decades of automated biological and chemical assays.
Selection of high-quality sperm with thousands of parallel channels
Selection of high-quality sperm with thousands of parallel channels† Mohammad Simchi, a Jason Riordon, a Jae Bem You, a Yihe Wang,a Sa Xiao,a Alexander Lagunov,b Thomas Hannam,b Keith Jarvi,c Reza Nosrati *d and David Sinton *a Author affiliations * Corresponding authors a Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, Canada E-mail: sinton@mie.utoronto.ca b Hannam Fertility Centre, 160 Bloor St. E, Toronto, Ontario,...
FertDish: microfluidic sperm selection-in-a-dish for intracytoplasmic sperm injection
FertDish: microfluidic sperm selection-in-a-dish for intracytoplasmic sperm injection† Sa Xiao, a Jason Riordon, a Mohammad Simchi, a Alexander Lagunov,b Thomas Hannam,b Keith Jarvi,c Reza Nosrati d and David Sinton *a Author affiliations * Corresponding authors a Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario M5S 3G8, Canada E-mail: sinton@mie.utoronto.ca b Hannam Fertility Centre, 160 Bloor Street East, Toronto, Ontario...
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