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A framework for evaluating the performance of SMLM cluster analysis algorithms - Nature Methods
Abstract Single-molecule localization microscopy (SMLM) generates data in the form of coordinates of localized fluorophores. Cluster analysis is an attractive route for extracting biologically meaningful information from such data and has been widely applied. Despite a range of cluster analysis algorithms, there exists no consensus framework for the evaluation of their performance.
Optimising a coordinate ascent algorithm for the meta-analysis of test accuracy studies
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Clinical scores in primary care
A clinical prediction rule represents a distillation of measurable features, usually by regression modelling. It helps standardise the approach to diagnosis and, in theory, should reduce variation in diagnosis and inappropriate prescribing. Our review compared Centor’s score with McIsaac’s score.1 These are the two most recommended prediction rules used for diagnosing GABHS-related pharyngitis in different national guidance.2,3 Although other scores such as Walsh’s …
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