Mohsen Akbaribazm

1 Introduction Breast cancer constitutes one of the most prevalent malignancies among women globally, representing 25% of cancer diagnoses and 15% of cancer-related mortality, with significant prevalence observed in Iran. Conventional therapies primarily involve mastectomy and chemotherapeutic agents, though these approaches face challenges including frequent tumor recurrence from residual foci in lymph nodes (Xiong et al. 2025).

1 INTRODUCTION A giant cell tumor (GCT) is a benign neoplasm characterized by progressive and destructive features. Typically manifesting in individuals during their third or fourth decade of life, GCT exhibits a higher prevalence in women than in men.

1 INTRODUCTION Oto-tricho, also known as a disorder related to the growth of hair follicles in the tympanic membrane (TM), is a rare condition that affects the TM and middle ear canal, potentially leading to hearing loss and tinnitus.