Mohsen Ghanbari
Rotterdam
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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
The blood metabolome of brain health in midlife and influences of genes, microbiome and exposome
Abstract Metabolic alterations are increasingly implicated in neurological disorders, including Alzheimer’s disease (AD), highlighting the relevance of the peripheral metabolome, shaped by genetic and environmental exposures, for brain health.
Combined genome-wide association study of facial traits in Europeans increases explained variance and improves prediction - Nature Communications
Abstract Facial appearance, one of the most recognizable and heritable human traits, exhibits substantial variation across individuals within and between populations due to its complex genetic underpinning, which remains largely elusive. Here, we report a combined genome-wide association study (C-GWAS) of 946 facial features derived from 44 landmarks obtained from 3D digital facial images of 11,662 individuals of European descent.
Meta-Analysis of Genome-Wide Association Studies Identifies Ancestry-Specific Associations Underlying Circulating Total Tau Levels
Abstract Circulating total-tau levels can be used as an endophenotype to identify genetic risk factors for tauopathies and related neurological disorders. Here, we confirmed and better characterized the association of the 17q21 MAPT locus with circulating total-tau in 14,721 European participants and identified three novel loci in 953 African American participants (4q31, 5p13, and 6q25) at P < 5 × 10-8.
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