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Mojtaba Akbari on Muck Rack

Mojtaba Akbari

As seen in: Nature, Wiley Online Library, Frontiers, Taylor & Francis Online, The Lancet
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Articles

Comparative study on the drug interaction with UiO-based MOFs by molecular dynamics simulation

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By Mojtaba Akbari, Fatemeh Moosavi Baigi
| Taylor & Francis Online
Abstract Efficient chemotherapy drug delivery remains a major challenge in cancer treatment, requiring carriers that optimize adsorption, diffusion, and controlled release. In this study, molecular dynamics simulation was used to investigate the diffusion and accumulation of three chemotherapy agents—5-fluorouracil (5-FU), gemcitabine (GEM), and curcumin (CUR)—within four zirconium-based metal-organic frameworks (MOFs): UiO-66, UiO-67, UiO-68, and MOF-1004.
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Prevalence of nosocomial infections and antibiotic resistance patterns in Iranian hospitals over five years - Scientific Reports

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By Masoumeh Beig, Mohammad Ibnu Sholeh, Reza Fadaei Nobari, Zohreh Abbaspour, Mojtaba Akbari, Mansour Siavash, Ramesh Hosseinkhani, Hamid Solgi
| Nature Verified
Abstract Hospital-acquired infections (HAIs) are a global concern for patient safety and healthcare quality. In Iran, the prevalence of HAIs and rising antibiotic resistance among key pathogens pose significant challenges to patient care and healthcare systems. This study examines the prevalence of HAIs, resistance patterns, and infection rates in Iranian hospitals from 2019 to 2023.
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Effectiveness of topical gabapentin cream in treating pruritus in dialysis patients: A randomized controlled trial

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By Gita Faghihi, Parisa Mohammadian, Bahareh Abtahi-Naeini, Mojtaba Akbari
| Wiley Online Library Verified
Introduction Gabapentin is an antiepileptic drug that alleviates neuropathic pain. Its oral use reduces the intensity of pruritus in patients receiving chronic dialysis therapy. However, it could lead to toxicity because of the patients' renal deficiency. In this study, we assessed the use of gabapentin topical in treating pruritus in dialysis patients. Methods This randomized, triple-blinded trial was performed on 80 patients divided into two groups randomly (40 in each group).
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