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Articles by Mojtaba Lotfaliany
Diet quality and depressive symptoms in older adults, assessing the effect modification by genetic predisposition and low-grade inflammation: a target trial emulation
Abstract Longitudinal studies have shown an association between diet quality and depression. However, reverse causality, unmeasured confounding, and selection bias remained important limitations. We aim to examine the relationship between diet quality and depression in older adults while addressing these issues and explore modification role of genetic predisposition to depression and low-grade inflammation. We emulated a target trial of dietary interventions using data from the ASPREE cohort.
Investigating Dietary Polyphenol Intake in the Australian Population: Results From the 2011–12 National Nutrition and Physical Activity Survey
AUSNUT: 2011-13 2011–13 Australian Food and Nutrient Database DUHREC Deakin University Human Research Ethics Committee FSANZ Food Standards Australia New Zealand IQR interquartile range NNPAS National Nutrition and Physical Activity Survey SD standard deviation USDA US Department of Agriculture 1 Introduction Polyphenols are a broad term describing a group of secondary metabolites synthesised by plants.
Potential Impact of Childhood Abuse on Quality of Life During Mood‐Stabilising Treatment in Individuals Living With Bipolar Disorder
1 Introduction Suboptimal treatment outcomes, including reductions in quality of life, remain common among people living with bipolar disorder [1, 2]. Identifying factors that can facilitate better treatment outcomes is clinically important [3, 4]. Experiences of abuse in childhood (i.e., ‘childhood abuse’) are known to negatively affect the course of bipolar disorder [5, 6].
Temporal Dynamics and Bidirectional Longitudinal Association Between Physical Function and Depressive Symptoms in Older Adults
1 Introduction Physical function is a critical component of healthy ageing and a key indicator of health status in older adults [1]. Declines in physical function, such as lower gait speed and weak handgrip strength, are diagnostic features of severe sarcopenia and are markers of frailty [2]. As people get older, significant physical changes occur, including muscle weakness, slowness, lower reserve capacity and osteoporosis [3].
Polyphenol intake and depressive symptoms in young adults: Evidence from a population-based longitudinal study
Accepted manuscript Polyphenol intake and depressive symptoms in young adults: Evidence from a population-based longitudinal study Published online by Cambridge University Press: 26 December 2025 Elizabeth Gamage Affiliation: Deakin University, IMPACT – the Institute for Mental and Physical Health and Clinical Translation, Food & Mood Centre, School of Medicine, Barwon Health, Geelong, Australia Melissa M Lane Affiliation: Deakin University, IMPACT – the Institute for Mental and Physical...
The association between flavonoid intake and first clinical diagnosis of central nervous system demyelination: a case-control study
Keywords multiple sclerosis nutrition diet flavonoids biophenols polyphenol 1 Introduction Multiple sclerosis (MS) is a neuroinflammatory/neurodegenerative disease characterized by demyelination and clinically presents as neurologic dysfunction. (Reich et al., 2018) While the cause of MS is yet to be fully elucidated, emerging research has implicated lifestyle and environmental risk factors including smoking, Epstein-Barr virus, low sunlight exposure, and low vitamin D status.
Food- vs. supplement-based very-low-energy diets and gut microbiome composition in women with high body mass index: A randomized controlled trial
Keywords gut microbiome very-low-energy diet dietary intervention randomized controlled trial obesity women food processing alpha diversity beta diversity taxonomic composition Introduction The gut microbiome is intricately connected to human health and disease, and understanding the influence of diet on its composition and function may inform gut-focused treatment strategies.1 The gut microbiome is shaped by both short- and long-term dietary exposures.2,3,4,5 Dietary interventions, including...
Pharmacotherapy in Comorbid Bipolar Disorder and Post‐Traumatic Stress Disorder From the STEP‐BD Cohort
1 Introduction Post-traumatic stress disorder (PTSD) is one of the most common mental disorders, with a prevalence rate of up to 8% in the general population [1-3]. PTSD is a multidimensional disorder with numerous biological underpinnings and several psychopathological characteristics [4, 5] PTSD is even more prevalent in individuals who also experience bipolar disorder (BD), with research showing that between 7% and 55% of those with BD experience comorbid PTSD [6-10].
The effects of food-based versus supplement-based very low-energy diets on gut microbiome composition and health outcomes in women with high body mass index (The MicroFit Study): a randomised controlled trial
MML is Secretary for the Melbourne Branch Committee of the Nutrition Society of Australia (unpaid) and has received travel funding support from the International Society for Nutritional Psychiatry Research, the Nutrition Society of Australia, the Australasian Society of Lifestyle Medicine, and the Gut Brain Congress.
Development of a harmonized sociodemographic and clinical questionnaire for mental health research: A Delphi-method-based consensus recommendation
Introduction Sociodemographic, clinical and behavioral factors play a crucial role in shaping mental health outcomes and can significantly impact the course, prognosis and response to treatment in mental disorders (Cai et al., 2022). Despite their importance, these factors are often inadequately described and inconsistently assessed across clinical trials.
El alto consumo de alimentos ultraprocesados se asocia con una elevada angustia psicológica como indicador de depresión
Pocos estudios han probado las asociaciones longitudinales entre el consumo de alimentos ultraprocesados y los resultados depresivos. Como tal, se necesita más investigación y replicación. El objetivo de este estudio es examinar las asociaciones entre la ingesta de alimentos ultraprocesados y el malestar psicológico elevado como indicador de depresión después de 15 años. Método Se analizaron los datos del Estudio de cohorte Colaborativo de Melbourne (MCCS) ( n = 23, 299).
Interpersonal Trauma and Depression Severity in Bipolar Disorder
menu This work may not be copied, distributed, displayed, published, reproduced, transmitted, modified, posted, sold, licensed, or used for commercial purposes. By downloading this file, you are agreeing to the publisher’s Terms & Conditions. Original Research Anna L. Wrobel, PhDa,b; Samantha E. Russell, BHealth&MedSc(Hons)a; Anuradhi Jayasinghe, MAb,c; Mojtaba Lotfaliany, PhDa; Alyna Turner, PhDa,d,*; Olivia M. Dean, PhDa,e; Sue M. Cotton, PhDb,f; Claudia Diaz-Byrd, MSg; Anastasia K.
Peri-Operative Risk Factors Associated with Post-Operative Cognitive Dysfunction (POCD): An Umbrella Review of Meta-Analyses of Observational Studies
4. Discussion This is the first umbrella review to provide a comprehensive overview of the observational data assessing the risk factors associated with post-operative cognitive dysfunction (POCD). The strongest evidence supports class III (“suggestive”) associations between pre-operative age and pre-operative diabetes (both in coronary artery bypass surgery) and increased risk of POCD. This umbrella review comprised 73 risk factors in a total population of 67,622 participants.
Nutrients | Free Full-Text | Higher Ultra-Processed Food Consumption Is Associated with Greater High-Sensitivity C-Reactive Protein Concentration in Adults: Cross-Sectional Results from the Melbourne Collaborative Cohort Study
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Melissa M. Lane 1,*, Mojtaba Lotfaliany 1, Malcolm Forbes 1,2,3, Amy Loughman 1, Tetyana Rocks 1, Adrienne O’Neil 1, Priscila Machado 4,5, Felice N.
Prevalence of normal weight obesity and its associated cardio-metabolic risk factors - Results from the baseline data of the Kerala Diabetes Prevention Program (KDPP)
Loading metrics Open Access Peer-reviewed Research Article Nitin Kapoor , Mojtaba Lotfaliany, Thirunavukkarasu Sathish, Kavumpurathu R. Thankappan, Nihal Thomas, John Furler, Brian Oldenburg, Robyn J. Tapp Nitin Kapoor, Mojtaba Lotfaliany, Thirunavukkarasu Sathish, Kavumpurathu R. Thankappan, Nihal Thomas, John Furler, Brian Oldenburg, Robyn J.
Effect of a Peer-led Lifestyle Intervention on Individuals With Normal Weight Obesity: Insights From the Kerala Diabetes Prevention Program
Highlights • Normal weight obesity is an under-recognized phenotype in the south Asian population. • Individuals with normal weight obesity (NWO) have a high cardiovascular mortality. • This data provides the first evidence regarding management of individuals with NWO. • A peer-led lifestyle intervention in them may minimally improve some risk factors. • NWO individuals are either inherently resistant or need more time to respond.
Effect of cardiac rehabilitation on 24-month all-cause hospital readmissions: A prospective cohort study:
1. Sangu, PV, Ranasinghe, I, Aliprandi Costa, B. Trends and predictors of rehospitalisation following an acute coronary syndrome: Report from the Australian and New Zealand population of the Global Registry of Acute Coronary Events (GRACE). Heart 2012; 98: 1728–1731. Google Scholar | Crossref | Medline 2. Centres for Medicare and Medicaid Services .
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