Morgan H Sono

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Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA Polymerase II productive elongation.

Dec 30, 2023 |

By Karen G Cornejo, Andie Venegas, Morgan H Sono, Madeline Door

| biorxiv.org

Abstract Signal-dependent RNA Polymerase II (Pol2) productive elongation is an integral component of gene transcription, including those of immediate early genes (IEGs) induced by neuronal activity. However, it remains unclear how productively elongating Pol2 overcome nucleosomal barriers.

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Morgan H Sono

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Activity-assembled nBAF complex mediates rapid immediate early gene transcription by regulating RNA Polymerase II productive elongation.

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