Motiur Rahaman

Abstract Genetic disorders such as HbE/β-thalassemia (HBT), though deleterious, may undergo positive selection in regions of high parasitic-endemicity, shaping infection outcomes.

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4. Iron Chelators Since all β-thalassemic patients, regardless of their transfusion dependency or non-dependency, acquire iron overload, it is imperative to employ iron chelators to eliminate the excess of toxic iron in them and, thus, alleviate the symptoms of iron overload.