Motomasa Furuse on Muck Rack

Motomasa Furuse

As seen in: MDPI
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Brain Sciences | Free Full-Text | Actin Alpha 2, Smooth Muscle (ACTA2) Is Involved in the Migratory Potential of Malignant Gliomas, and Its Increased Expression at Recurrence Is a Significant Adverse Prognostic Factor

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By Takumi Hoshimaru, Naosuke Nonoguchi, Takuya Kosaka, Motomasa Furuse
| MDPI
1. Introduction Malignant gliomas are characterized by aggressive tumor cell proliferation and a poor prognosis despite treatments, such as surgical resection, radiotherapy, and chemotherapy, with reported 5-year survival rates of approximately 4.7–10.1% for World Health Organization (WHO) grade 4 glioblastomas (GBM) [1,2]. Patients with malignant gliomas present with frequent recurrences not only locally but also in distant areas of the brain [3].
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