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Articles by Mu Chen
All-optical leaky integrate-and-fire neuron in a thin-film lithium niobate micro-ring
Optical neuromorphic computing provides a highly efficient information-processing paradigm but entails several physical trade-offs. Laser-based spiking neurons exhibit fast reset capabilities but suffer from low integration density. Meanwhile, micro-ring resonators or phase-change material-based devices show better integration but lack efficient intrinsic reset mechanisms.
Photorealistic 3D Holographic Display with Natural Defocus Effect
Abstract Holographic displays deliver realistic visual experiences by reconstructing three-dimensional (3D) light fields. However, widely used RGB-D data offers reliable geometry only in focused regions, lacking light field information in defocused areas, particularly with transparent or reflective surfaces. Existing methods typically utilize coherent diffraction to approximate defocus effects in incoherent perception, introducing ringing artifacts and unnatural depth transitions.
Administrative-driven hierarchical management of atrial fibrillation on cardiovascular events: a prospective matched cohort study - Nature Communications
Abstract The administrative-driven hierarchical management (ADHM) refers to the management model that general practitioners act as “voluntary gatekeepers” under local government policy incentives in the non-mandatory hierarchical medical system. However, the impact of ADHM of atrial fibrillation (AF) on cardiovascular events remains unclear. We enrolled 1455 patients with AF in the ADHM cohort and 7275 in the matched usual care (UC) cohort in Shanghai, China.
Comprehensive compensation of real-world degradations for robust single-pixel imaging - Light: Science & Applications
Abstract Single-pixel imaging (SPI) faces significant challenges in reconstructing high-quality images under complex real-world degradation conditions. This paper presents an innovative degradation model for the physical processes in SPI, providing the first comprehensive and quantitative analysis of various SPI noise sources encountered in real-world applications. Especially, pattern-dependent global noise propagation and object jitter modelling methods for SPI are proposed.
Electrochemical Late‐Stage Stitching of Tryptophan Peptides via N─S Bond Formation
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Exploration potential sepsis–ferroptosis mechanisms through the use of CETSA technology and network pharmacology - Scientific Reports
Abstract As an important self-protection response mechanism of the body, inflammation can not only remove the necrotic or even malignant cells in the body, but also take a series of targeted measures to eliminate the pathogen of foreign invasion and block the foreign substances that may affect the life and health of the body. Flavonoids have known anti-inflammatory, anti-oxidation, anti-cancer and other effects, including glycyrrhizin molecules is one of the representatives.
Synthesis and Properties of Site-Specific Acetylated Anthocyanins: Focusing on Cyanidin-3-O-glucoside and Malvidin-3-O-glucoside
Food and Beverage Chemistry/BiochemistryApril 4, 2025 Jun Hu School of Chemical Engineering and Light Industry, Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, Guangdong University of Technology, Guangzhou 510632, China Chujie Liang School of Chemical Engineering and Light Industry, Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, Guangdong University of Technology, Guangzhou 510632, China Jinchao Xiao Department of Food Science and Engineering,...
Nonlocal Huygens’ meta-lens for high-quality-factor spin-multiplexing imaging - Light: Science & Applications
Abstract Combining bright-field and edge-enhanced imaging affords an effective avenue for extracting complex morphological information from objects, which is particularly beneficial for biological imaging. Multiplexing meta-lenses present promising candidates for achieving this functionality.
Advancing wavefront sensing: meta Shack-Hartmann sensor enhances phase imaging - Light: Science & Applications
Abstract A meta-lens array-based Shack-Hartmann wavefront sensor has been developed to break the limits imposed by the size and curvature of traditional micro-lenses, which significantly improves both sampling density and angular resolution of phase measurement. Metasurface advances the field of optical phase measurement to smaller-scale complex wavefront characterization.
Nonlocal meta-lens with Huygens’ bound states in the continuum - Nature Communications
Abstract Meta-lenses composed of artificial meta-atoms have stimulated substantial interest due to their compact and flexible wavefront shaping capabilities, outperforming bulk optical devices. The operating bandwidth is a critical factor determining the meta-lens’ performance across various wavelengths.
1β-Hydroxydeoxycholic Acid as an Endogenous Biomarker in Human Plasma for Assessment of CYP3A Clinical Drug-Drug Interaction Potential
Abstract 4β-Hydroxycholesterol (4β-HC) in plasma has been used as a biomarker to assess CYP3A drug-drug interaction (DDI) potential during drug development. However, due to the long half-life and narrow dynamic range of 4β-HC, its use has been limited to the identification of CYP3A inducers, but not CYP3A inhibitors.
Prognostic Impact of Left Atrial Appendage Patency After Device Closure
BACKGROUND: The prognostic impact of left atrial appendage (LAA) patency, including those with and without visible peri-device leak (PDL), post–LAA closure in patients with atrial fibrillation, remains elusive. METHODS: Patients with atrial fibrillation implanted with the WATCHMAN 2.5 device were prospectively enrolled. The device surveillance by cardiac computed tomography angiography was performed at 3 months post-procedure.
Sustainability | Free Full-Text | Application of Femtosecond Laser Processing Method in the Sustainable Conservation of Stone Cultural Relics: An Example of Green Schist in Wudang Mountain, China
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A Multi-Hazard Risk Assessment Model for a Road Network Based on Neural Networks and Fuzzy Comprehensive Evaluation
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Photonic Meta‐Neurons (Laser Photonics Rev. 18(3)/2024)
Graphical Abstract Photonic Meta-Neuron In article number 2300456, Xiaoyuan Liu, Mu Ku Chen, and Din Ping Tsai introduce the “Photonic Meta-Neuron”, a groundbreaking concept combining meta-optics and neurobiology. With a biomimetic hierarchical structure, the meta-neuron exhibits outstanding in-memory computing capabilities, emphasizing high-speed performance and energy efficiency.
Quasiparticle scattering in three-dimensional topological insulators near the thickness limit
In the ultrathin regime, Bi2Te3 films feature two surfaces (with each surface being a two-dimensional Dirac-fermion system) with complicated spin textures and a tunneling term between them. We find in this regime that the quasiparticle scattering is completely different compared with the thick-film case and even behaves differently at each thickness. The thickness-dependent warping effect and tunneling term are found to be the two main factors that govern the scattering behaviors.
Experiencias de nuevas enfermeras durante la fase aguda de la pandemia del COVID-19 en los Estados Unidos
Experiencias de nuevas enfermeras durante la fase aguda de la pandemia del COVID-19 en los Estados Unidos Christine D. Byrne [1] ; Linda Carman Copel [1] ; Suzanne C. Smeltzer [1] ; Mu-Hsun Chen [2] [1] Universidad de Villanova, Facultad de Enfermería M. Louise Fitzpatrick, Villanova, Pensilvania, EE.UU [2] Departamento de Matemáticas y Estadística, Universidad de Villanova, Villanova, Pensilvania, EE.
Computational simulation of multi-wavelength light-field thermometry based on a chromatic meta-lens
This Letter proposes a light-field meta-lens multi-wavelength thermometry (MMT) system that is capable of modulating a full-spectrum incident radiation into four separate wavelength beams. The chromatic meta-lens is designed using finite-difference time-domain (FDTD) software to function as a filter, ensuring its ability to separate four wavelengths.
Full-Matrix Imaging in Fourier Domain towards Ultrasonic Inspection with Wide-Angle Oblique Incidence for Welded Structures
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Bound States in the Continuum for Hot Electron Generation in Integrated-Resonant Metasurfaces
Download Hi-Res ImageDownload to MS-PowerPointCite This:J. Phys. Chem. C 2024, XXXX, XXX This article has not yet been cited by other publications.
Nanoimprint Meta‐Device for Chiral Imaging
1 Introduction Nature has honed elegant survival strategies through billions of years of natural selection.[1] For instance, the mantis shrimp exemplifies the utilization of circularly polarized light for communication, predator evasion, and enhanced mating success in the vast ocean.[2] Human perception is inherently limited by the physiological structure and neural mechanisms, restricting the perception of the external world to a finite set of sensory channels.[3] Recent research has focused...
China rapidly introduced AIGC regulation, only to face heated discussion
As we previously shared, entrepreneurs, government officials, investors, and scholars in China have paid close attention to generative AI in an effort to catch up with the US. One area where China has acted quickly is in regulating generative AI.
Frontiers | The impact of empirical Marshall vein ethanol infusion as a first-choice intraoperative strategy on the long-term outcomes in patients with persistent atrial fibrillation undergoing mitral isthmus ablation
1. Introduction Mitral isthmus (MI)-dependent conduction has been considered one of the most important substrates in persistent atrial fibrillation (PeAF) (1). In most cases, bidirectional block of MI could not be achieved only with endocardial catheter ablation (CA), even with supplementary epicardial ablation from the distal coronary sinus (CS).
Planar focusing lens for enhanced far-field ultrasonic imaging
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A Meta‐Device for Intelligent Depth Perception
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202107465-sup-0001-SuppMat.pdf3.2 MB Supporting Information References 1, , , IEEE Conf. on CCVPR, Honolulu, HI 2017. 2, , , , IEEE Conf. on CVPR, Honolulu, HI 2017. 3, , , , J. Text. Inst. 2016, 107, 12. 4, , , , , , Remote Sens. 2017, 9, 508. 5, , , , , , , IEEE Conf. on CVPR, Boston, MA 2015. 6, , , IEEE Trans. Pattern Anal. Mach. Intell. 2016, 39, 287. 7, Adv. Opt. Photonics 2011, 3, 128. 8, Opt.
Impaired pulmonary function in discharged patients with COVID-19: more work ahead
Ruchong Chen, Yi Gao, Mu Chen, Wenhua Jian, Chunliang Lei, Jinping Zheng, Shiyue Li European Respiratory Journal 2020 56: 2002194; DOI: 10.1183/13993003.02194-2020 Abstract Impairment of diffusion capacity is the most common abnormality in discharged patients with COVID-19. Both decreased alveolar volume and KCO contribute to the pathogenesis of impaired diffusion capacity. More follow-up work is needed.
Impaired pulmonary function in discharged patients with COVID-19: More work ahead
Ruchong Chen, Yi Gao, Mu Chen, Wenhua Jian, Chunliang Lei, Jinping Zheng, Shiyue Li European Respiratory Journal 2020; DOI: 10.1183/13993003.02194-2020 Abstract Impairment of diffusion capacity is the most common abnormality in discharged patients with COVID-19. Both decreased alveolar volume and KCO contribute to the pathogenesis of impaired diffusion capacity. More work ahead for follow-up is needed.
Abnormal pulmonary function in COVID-19 patients at time of hospital discharge
Xiaoneng Mo, Wenhua Jian, Zhuquan Su, Mu Chen, Hui Peng, Ping Peng, Chunliang Lei, Ruchong Chen, Nanshan Zhong, Shiyue Li European Respiratory Journal 2020 55: 2001217; DOI: 10.1183/13993003.01217-2020 Abstract In discharged survivors with COVID-19, impairment of diffusion capacity is the most common abnormality of lung function, followed by restrictive ventilatory defects, which are both associated with the severity of the disease https://bit.ly/2yUaBaT To the Editor: On 11 March 2020, the...
Nanoparticles Na4Ni3Р4О15-Ni(OH)2 Core-Shell as hybrid electrocatalyst for the oxygen evolution reaction in alkaline electrolyte
Nanoparticles Na4Ni3Р4О15-Ni(OH)2 Core-Shell as hybrid electrocatalyst for the oxygen evolution reaction in alkaline electrolyte There are wide interests in developing efficient, robust and low-cost electrode materials for electrolysis of water to produce clean hydrogen fuel. It is especially important to improve the performance and durability of electrocatalysts for OER.
Selective trapping of hexagonally warped topological surface states in a triangular quantum corral
Abstract The surface of a three-dimensional topological insulator (TI) hosts two-dimensional massless Dirac fermions (DFs), the gapless and spin-helical nature of which leads to their high transmission through surface defects or potential barriers.
Achromatic metalens array for full-colour light-field imaging
Abstract A light-field camera captures both the intensity and the direction of incoming light1,2,3,4,5. This enables a user to refocus pictures and afterwards reconstruct information on the depth of field. Research on light-field imaging can be divided into two components: acquisition and rendering. Microlens arrays have been used for acquisition, but obtaining broadband achromatic images with no spherical aberration remains challenging.
A novel LC-MS/MS assay to quantify dermatan sulfate in cerebrospinal fluid as a biomarker for mucopolysaccharidosis II
Analytical method for the determination of disaccharides derived from keratan, heparan, and dermatan sulfates in human serum and plasma by high-performance liquid chromatography/turbo ionspray ionization tandem mass spectrometry 368(1), 79–86 (). •• Describes an orthogonal LC–MS platform that separates native glycosaminoglycans disaccharides without the use of labeling. Crossref
Dairy consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis
In three prospective cohorts of US men and women, we found that intakes of total dairy products were not significantly associated with the risk of T2D, but higher consumption of yogurt was significantly associated with a lower risk. An updated meta-analysis of our cohorts and published literature suggest a marginally lower risk of T2D with higher dairy consumption and a consistent inverse association between yogurt consumption and T2D risk.
An ultra-sensitive LC-MS/MS method to determine midazolam levels in human plasma: development, validation and application to a clinical study
An ultra-sensitive LC–MS/MS method to determine midazolam levels in human plasma: development, validation and application to a clinical study Aim: Midazolam is a commonly used marker substrate for the in vivo assessment of CYP3A activity. Reliable pharmacokinetic assessment at sub-pharmacological doses of midazolam requires an ultra-sensitive analytical method.
Transferring the bendable substrateless GaN LED grown on a thin C-rich SiC buffer layer to flexible dielectric and metallic plates
By growing an epitaxial GaN LED on C-rich a-SiC buffer deposited SiO /Si substrate, the simplified transfer to versatile flexible metallic/dielectric membranes is demonstrated. Both the high growth temperature at 1000 °C and the slow deposition rate played important roles in the meticulous MOCVD growth of n-GaN along the surface normal of the a-SiC at the very beginning.
Transferring the Bendable Substrateless GaN LED Grown on Thin C-rich SiC Buffer Layer to Flexible Dielectric and Metallic Plates
By growing the epitaxial GaN LED on C-rich a-SiC buffer deposited SiO /Si substrate, the simplified transfer to versatile flexible metallic/insulated membranes is demonstrated. Both the high growth temperature at 1000 C and the slow deposition rate have played important roles for meticulous MOCVD growth of n-GaN along the surface normal of the a-SiC at very beginning.
Dairy fat and risk of cardiovascular disease in 3 cohorts of US adults
Background: Few prospective studies have examined dairy fat in relation to cardiovascular disease (CVD). Objective: We aimed to evaluate the association between dairy fat and incident CVD in US adults. Design: We followed 43,652 men in the Health Professionals Follow-Up Study (1986–2010), 87,907 women in the Nurses’ Health Study (1980–2012), and 90,675 women in the Nurses’ Health Study II (1991–2011).
Effect of low-fat diet interventions versus other diet interventions on long-term weight change in adults: a systematic review and meta-analysis
1. Hooper L Abdelhamid A Moore HJ Douthwaite W Skeaff CM Summerbell CD Effect of reducing total fat intake on body weight: systematic review and meta-analysis of randomised controlled trials and cohort studies. BMJ. 2012; 345: e7666 2. Johnston BC Kanters S Bandayrel K et al. Comparison of weight loss among named diet programs in overweight and obese adults: a meta-analysis. JAMA. 2014; 312: 923-933 3. Sacks FM Bray GA Carey VJ et al.
Putting RSV Back on the Radar
Adults usually experience symptoms of the common cold - runny nose, sneezing, coughing, and fever. However, in infants and young children, the symptoms can be much more serious. In addition to being tired and fussy, they may not want to eat and may have problems breathing. If this happens, the child should seek immediate medical care. Even when hospitalized, the vast majority of children survive without any complications. However in the elderly, RSV causes 10,000 deaths or more annually in the US.
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