Mubark D. Mebrat

Introduction Click to copy section linkSection link copied! Transient receptor potential melastatin member 8 (TRPM8) is a polymodally activated ion channel that functions as the primary human cold sensor and is activated by menthol and other cooling compounds. (1−3) TRPM8 has been implicated in pain, cancer, obesity, and other pathophysiologies. (4−9) As a result, TRPM8 has garnered interest as a promising target for a variety of relevant clinical indications.

Research ArticleImaging Lei G. Wang1,*, Connor W. Barth1,*, Catherine H. Kitts1, Mubark D. Mebrat1, Antonio R. Montaño1, Broderick J. House1, Meaghan E. McCoy1, Alexander L. Antaris2, S. N. Galvis2, Ian McDowall2, Jonathan M. Sorger2 and Summer L. Gibbs1,3,4,† 1Biomedical Engineering Department, Oregon Health & Science University, Portland, OR 97201, USA. 2Intuitive Surgical, Sunnyvale, CA 94086, USA. 3Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97201, USA.