Reviewed by Susha Cheriyedath, M.Sc. A non-viral lipid nanoparticle system delivered three RNA editing components to liver cells, suggesting a preclinical path toward precise, repeat-dose correction of inherited metabolic diseases. AI-generated illustration created using ChatGPT/OpenAI, inspired by the PE-LNP formulation and administration workflow described in Jiang et al. (2026). Original research: Jiang, A.Y., Cristian, A., Brooks, D.L., et al.