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Muhammad Sadeqi Nezhad on Muck Rack

Muhammad Sadeqi Nezhad

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Articles

UNC5B regulates epithelial-to-mesenchymal transition through a SRC-ZEB1 signaling axis to facilitate pancreatic cancer metastasis

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By Chris Harris, Orjola Prela, Wade Narrow, Mitchell Breitenbach, Lan Wang, Jennifer Becker, Buket Bagci, Yansheng Hao, Scott Gerber, Stephano S. Mello, Tracy Withers Verified, Darren Carpizo, Muhammad Sadeqi Nezhad, Shubhrika Jain, Aram F. Hezel
| Nature Verified
Abstract Metastatic dissemination is the principal cause of death in pancreatic ductal adenocarcinoma (PDAC), yet the molecular determinants that enable this process remain poorly understood. Here, we identify the axon guidance receptor UNC5B as a central regulator of PDAC metastasis.
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