Mumingjiang Munisha

Abstract Abnormal placentation drives many pregnancy-related pathologies and poor fetal outcomes, but the underlying molecular causes are understudied. Here, we show that persistent replication stress due to mutations in the MCM2-7 replicative helicase disrupts placentation and reduces embryo viability in mice. MCM-deficient embryos exhibited normal morphology but their placentae had a drastically diminished junctional zone (JZ).

South Carolina Congressional Delegation has requested the highest level of funding possible for the Charleston Harbor Deepening Project.Though USACE allocated $17.5 million to the work plan in 2017, congressmen are asking for $90 million in the 2018 Fiscal Year work plan.The request was signed by Senators Lindsey Graham, and Tim Scott, and Representatives Mark Sanford, Joe Wilson, Jeff Duncan, Trey Gowdy, Ralph Norman, James Clyburn and Tom Rice.Congressmen wrote to Secretary James and...