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Murtaza Barkarar on Muck Rack

Murtaza Barkarar

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Articles

Oxidative stress-responsive cell wall remodeling depends on phosphate in Candida albicans

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By Anand Jacob, Wanjun Qi, Jayasubba Reddy Yarava, Josh V Vermaas, Julia Köhler, Tuo Wang, Murtaza Barkarar, Alicia Withrow, Aswath Karai
| Nature Verified
Abstract The growing number of patients susceptible to invasive Candida albicans infections has intensified the need for effective antifungal targets in pathways essential for fungal growth and pathogenesis. Among these pathways, phosphate homeostasis has emerged as a significant determinant of virulence, yet how phosphate availability shapes cell wall structure in response to host-derived oxidative stress remains unclear. During commensal growth, C.
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