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Proteomic analysis of extracellular vesicles derived from canine mammary tumour cell lines identifies protein signatures specific for disease state - BMC Veterinary Research
The following canine mammary cell lines were used: one non-neoplastic cell line (MTH53A, used as a healthy control), one simple adenoma cell line (ZMTH3), one simple carcinoma cell line (MTH52C) and two complex carcinoma cell lines (1305, DT1406TB).
Frontiers | The TiHoCL panel for canine lymphoma: a feasibility study integrating functional genomics and network biology approaches for comparative oncology targeted NGS panel design
1 Introduction Driven by plummeting costs, next-generation sequencing (NGS) has revolutionized biomedical research, playing an instrumental role in advancing our understanding of the molecular basis of various diseases (1). NGS has numerous applications, ranging from whole-genome (re)sequencing to targeted sequencing for variant identification or confirmation.
Tyrosine kinase inhibitors and molecularly driven therapeutic approaches for canine lymphoma: a systematic review and meta-analysis
Abstract Background: Canine lymphoma (cL), the second most common canine cancer after mammary carcinoma, presents therapeutic challenges due to limitations of conventional regimens, necessitating novel therapeutic approaches. Tyrosine kinase inhibitors (TKIs), which have demonstrated efficacy in human non-Hodgkin lymphoma (NHL), are increasingly being investigated as targeted therapies for cL, which also serves as a valuable translational model for NHL research.
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