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Articles

RAFT-Polymerized Thermoresponsive Glycopolymer-Grafted-Nanoparticles: Modulation of Lectin Binding

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By Mithun Chakraborty, Musti J. Swamy, Somdatta Rudra, Saradamoni Mondal
| dx.doi.org
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Glycopolymer-Grafted Nanoparticles: Synthesis Using RAFT Polymerization and Binding Study with Lectin

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By Rambabu Koyilapu, Debparna Datta, Ramu Sridhar Perali, Musti J. Swamy
| American Chemical Society
The weak binding between carbohydrates and proteins is a major constraint toward the development of carbohydrate-based therapeutics. To address this, here we report the synthesis of glycopolymer (GP)-grafted silica nanoparticles (SiNP) by using reversible addition–fragmentation chain transfer (RAFT) polymerization through the grafting-from approach using a multistep process.
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