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Muthu Panchanatham on Muck Rack

Muthu Panchanatham

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Articles

Procognitive restoration of PV neuron plasticity in neurodevelopmental disorders

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By Yu-Tzu Shih, Jason Bondoc Alipio, Zin-Juan Klaft, Nathaniel Green, Alok Nath Mohapatra, Travis D. Goode, Devesh Kumar Pathak, Lai Wong, Ruslan Sadreyev, Jung Hyun, Omar Ahmed, Chris G. Dulla, Amar Sahay, Muthu Panchanatham
| Nature Verified
Abstract The hippocampus forms memories of our experiences in populations of coactive pyramidal neurons (PNs)1,2,3. Fast-spiking parvalbumin-expressing inhibitory neurons (PV INs) in the dentate gyrus–CA3/CA2 circuit of the hippocampus precisely control PN activity through mossy fibre-dependent feedforward inhibition4,5,6,7,8,9,10,11.
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