My Co Tran

eLife Assessment The manuscript explores how bacterial evolution in the presence of lytic phages modulates b-lactams resistance and virulence properties in methicillin-resistant Staphylococcus aureus (MRSA). This important work improves our knowledge of how mutation in genes required for phage infection confers sensitivity to b-lactams and alter virulence properties. Altogether, the findings are convincing.

Abstract Bacteriophage (phage) therapy has been proposed as a means to combat drug-resistant bacterial pathogens. Infection by phage can select for mutations in bacterial populations that confer resistance against phage infection. However, resistance against phage can yield evolutionary trade-offs of biomedical use.

Sparganosis: an under-recognised zoonosis in Australia? Quoc (Ryan) Tran1, My Co Tran2 and Daniel Mehanna1 1 Surgical Department, Caboolture Hospital, Caboolture, Queensland, Australia 2 Dermatology, The University of Queensland Diamantina Institute, Brisbane, Queensland, Australia Correspondence to Quoc (Ryan) Tran, ryantran1001{at}gmail.com Abstract Sparganosis is a rare zoonotic parasitosis that is sporadically reported worldwide.