Nadia Bom Pedersen

1 Radioligand Therapy (RLT)—A Hope to Treat Cancers More Efficiently Over the last decade, RLT has attracted a lot of interest in oncology, as it has been shown to work where conventional treatment failed [1-4]. Recently, RLT has also been proven effective as first-line treatment. For example, the Phase III NETTER-2 trial—using the radiopharmaceutical 177Lu-Lutathera®—showed a 72% reduced risk of death compared to first-line treatment with octreotide long-acting release (Novartis, Jan.

PLOS ONE, Aug 2023 We describe a quantitative detection method for mutated microRNA in human plasma samples. Specific oligonucleotides designed from a Peyrard-Bishop model allowed accurate prediction of target:probe recognition affinity and specificity. Our amplification-free tandem bead-based hybridization assay had limit of detection of 2.2 pM.