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Nadila Airiken on Muck Rack

Nadila Airiken

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Articles

Targeting TWEAK to enhance mitochondrial biogenesis and attenuate age-related muscle mass loss

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By Zhuoya Maimaitiwusiman, Saiyare Xuekelati, Yanbin Xu, Shuke Guo, Yining Yang, Hongmei Wang, Anyan Wang, Nadila Airiken
| Nature Verified
Abstract Mitochondrial dysfunction is an important cause of sarcopenia, and TWEAK/Fn14, as one of the major muscle wasting cytokines, its role in the development of sarcopenia by regulating mitochondrial biogenesis remains unclear. Expression of TWEAK in old and young mice was both detected. TWEAK was silenced in C2C12 myocytes using lentiviral vectors.
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