Nadim Eghbarieh

1 Introduction Nature possesses a remarkable ability to construct bonds with precision, giving rise to molecules with defined geometries—a fundamental prerequisite for life.[1-3] The selective formation of multiple bonds, particularly carbon─carbon and carbon─heteroatom linkages,[4-7] is also central to advancing bioactive compounds,[8] materials science,[9-11] and natural products designing.[12, 13] Yet, despite their importance, synthetic strategies to access such complex architectures...

Diarylmethanes and diarylketones have attracted considerable interest due to their unique structural, chemical, and physical properties. (1−7) They are essential in the synthesis of natural products, bioactive compounds, (3) pharmaceuticals, (4) agrochemicals, and modern synthetic materials. (4,5,7,8) An important focus in organic synthesis is the modular and efficient construction of these scaffolds, particularly their unsymmetrical variants containing two distinct aryl groups.

Although diboron species, with a boron–boron single bond, have been recognized for approximately a century, their chemistry has undergone thorough explorations only in the last three decades. (1,2) These investigations revealed crucial structural features and reaction patterns, ultimately proving highly versatile and valuable in diverse synthetic pathways.