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Articles

Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation

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By Hu Kuan, Lin Wu Xie, Yiding Zhang, Nagatsu Kotaro
| Royal Society of Chemistry Verified
Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation Herein, a PD-L1 targeted native peptide was developed for PET imaging. 18F and 64Cu were utilized to label the peptide. To improve the pharmacokinetics and biodistribution of the tracers, the peptide was further pegylated to form star-like tetramers.
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