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Naial Haq on Muck Rack

Naial Haq

As seen in: BioRxiv
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Articles

Adherent reformed islets: a long-term primary cell-based platform for exploring mouse and human islet biology.

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By Maya Wilson, Margot Jacobs, Naial Haq, Klaudia Toczyska
| BioRxiv
Abstract Pancreatic islets are 3-dimensional micro-organs that maintain β-cell functionality via cell-cell and cell-matrix communication. Isolated primary islets are the gold standard for in vitro models. However, native islets present experimental challenges for long-term mechanistic studies owing to their short culture life (approximately 1 week). We developed a novel long-term protocol to study the function of primary islets.
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