Naihsin Hsiung

1 Introduction Diabetic wounds, as one of the most common and severe complications of diabetes, not only significantly reduce the quality of life of patients but also impose a huge socio-economic burden.[1-4] The pathological mechanism of diabetic wounds is highly complex, involving a multifactorial interplay of oxidative stress triggered by a persistently high-glucose microenvironment, chronic inflammation, impaired angiogenesis, abnormal extracellular matrix remodeling, and immune...