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Naiyi Yin

As seen in: Nature, ACS Publications
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Articles

Prenatal exposure to trace elements impacts mother-infant gut microbiome, metabolome and resistome during the first year of life - Nature Communications

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By Naiyi Yin, Xiaolin Cai, Shimao Xiong
| Nature Verified
Abstract Infancy is a critical window for the colonization of gut microbiome. However, xenobiotic impacts on gut microbiome development in early life remain poorly understood. Here, we recruit 146 mother-infant pairs and collect stool samples at 3, 6, and 12 months after delivery for amplicon sequencing (N = 353), metagenomics (N = 65), and metabolomics (N = 198). Trace elements in maternal hair samples (N = 119) affect diversity and composition of the infant gut microbiome.
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In Vitro Assessment of Arsenic Release and Transformation from As(V)-Sorbed Goethite and Jarosite: The Influence of Human Gut Microbiota

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By Naiyi Yin, Xiaolin Cai, Lirong Zheng, Huili Du
| ACS Publications
The importance of arsenic metabolism by gut microbiota has been evidenced in risk characterization from As exposures. In this study, we evaluated the metabolic potency of human gut microbiota toward As(V)-sorbed goethite and jarosite, presenting different behaviors of As release, and the solid–liquid transformation and partitioning. The release of As occurred mainly in the small intestinal phase for jarosite and in the colon phase for goethite, respectively.
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Estimation of the Bioaccessibility and Bioavailability of Fe, Mn, Cu, and Zn in Chinese Vegetables Using the In Vitro Digestion/Caco-2 Cell Model: the Influence of Gut Microbiota - Food & Function (RSC Publishing)

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By Xiaolin Cai, Xiaochen Chen, Naiyi Yin, Huili Du
| Royal Society of Chemistry Verified
The influence of human gut microbiota on the bioaccessibility and bioavailability of trace elements in vegetables has barely been studied. An in vitro digestion model combining the physiologically based extraction test (PBET) and the Simulator of Human Intestinal Microbial Ecosystem (SHIME) was applied.
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