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Frontiers | Adverse events related to drug–drug interactions in tocilizumab combination therapy: a retrospective analysis and clinical implications
Abstract Objective: Tocilizumab (TCZ) is widely used in the treatment of autoimmune diseases and usually needs to be combined with other drugs. However, limited evidence is available on TCZ drug–drug interactions (DDIs). This study aimed to identify and evaluate the adverse events (AEs) associated with DDIs between TCZ and co-administered drugs based on real-world clinical data to offer a reference basis for clinical decision-making.
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