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Nanees N. Soliman on Muck Rack

Nanees N. Soliman

As seen in: Nature
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Articles

Synthesis, antimicrobial evaluation, molecular docking, and drug-likeness assessment of novel phenothiazine chromene hybrid compounds

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By Nesma M. Bayoumy, Ahmed A. Fadda, Hatem E Gaffer, Nanees N. Soliman
| Nature Verified
Abstract By carefully hybridizing with scaffolds generated from chromene, pyranochromene, and cyanoacetamide, a novel class of phenothiazine-based heterocycles was created. IR, NMR, and MS investigations were used to establish the structural integrity of each molecule.
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Design, synthesis, molecular docking and cytotoxic evaluation of novel pyrimidine-based sulfonamide derivatives as potent anticancer agents: SAR insights and biological profiling

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By Ahmed A. Fadda, Hatem E Gaffer, Nanees N. Soliman, Nesma M. Bayoumy
| Nature Verified
Abstract The low selectivity and significant toxicity of current chemotherapeutic medicines make the research and development of novel anticancer agents an urgent necessity. This study used IR, NMR, MS, and elemental studies to rationally design, synthesize, and structurally characterize a novel class of pyrimidine-based sulfonamide derivatives.
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