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Nani Osada

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Association of Genetic Polymorphisms with Abdominal Aortic Aneurysm in the Processes of Apoptosis, Inflammation, and Cholesterol Metabolism

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By Monika Herten, Giovanni F. Torsello, Nyityasmono Tri Nugroho, Nani Osada
| MDPI
1. Introduction Abdominal aortic aneurysm (AAA) is a degenerative disease with a prevalence from 3.9 to 7.7% in the USA and Europe [1]. It mainly occurs in the last decades of life and predominantly affects the male gender [2]. A ruptured AAA leads to a high mortality rate of up to 80% [3,4]. The risk of developing AAA increases with hypertension, dyslipidemia, and a history of smoking [5,6].
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