Nani Van Gerven on Muck Rack

Nani Van Gerven

As seen in: Nature
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Articles

Cryo-EM analysis of the Bacillus thuringiensis extrasporal matrix identifies F-ENA as a widespread family of endospore appendages across the Firmicutes phylum

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By Mike Sleutel, Adrià Sogues, Nani Van Gerven, Unni Lise Jonsmoen
| biorxiv.org
Abstract For over 100 years, Bacillus thuringiensis (Bt) has been used as an agricultural biopesticide to control pests caused by insect species in the orders of Lepidoptera, Diptera and Coleoptera. Under nutrient starvation, Bt cells differentiate into spores and associated toxin crystals that can adopt biofilm-like aggregates.
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A dual-constriction biological nanopore resolves homonucleotide sequences with high fidelity

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By Han Remaut, Nani Van Gerven, Wim Jonckheere, Richard Hambley
| Nature Verified
Abstract Single-molecule long-read DNA sequencing with biological nanopores is fast and high-throughput but suffers reduced accuracy in homonucleotide stretches. We now combine the CsgG nanopore with the 35-residue N-terminal region of its extracellular interaction partner CsgF to produce a dual-constriction pore with improved signal and base-calling accuracy for homopolymer regions.
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