Nanine de Groot on Muck Rack

Nanine de Groot

As seen in: The Journal of Immunology
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Articles

Unravelling the architecture of Major Histocompatibility Complex class II haplotypes in rhesus macaques

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By Nanine de Groot, Ngoc Le, Jesse Bruijnesteijn, Ronald E. Bontrop
| biorxiv.org
Abstract The regions in the genome that encode components of the immune system are often featured by polymorphism, copy number variation and segmental duplications. There is a need to thoroughly characterize these complex regions to gain insight into the impact of genomic diversity on health and disease.
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Unparalleled Rapid Evolution of KIR Genes in Rhesus and Cynomolgus Macaque Populations

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By Jesse Bruijnesteijn, Nanine de Groot, Nel Otting, Ronald E. Bontrop
| The Journal of Immunology Verified
Jesse Bruijnesteijn, Nanine de Groot, Marit K. H. van der Wiel, Nel Otting, Annemiek J. M. de Vos-Rouweler, Natasja G. de Groot and Ronald E. Bontrop J Immunol April 1, 2020, 204 (7) 1770-1786; DOI: https://doi.org/10.4049/jimmunol.1901140 Key Points KIR genes evolved rapidly in closely related macaque species and their populations. Hybrid KIR genes in macaques are generated frequently by recombination.
Open in Who Shared Issue with article?

Unparalleled Rapid Evolution of KIR Genes in Rhesus and Cynomolgus Macaque Populations

|
By Jesse Bruijnesteijn, Nel Otting, Nanine de Groot, Ronald E. Bontrop
| The Journal of Immunology Verified
Jesse Bruijnesteijn, Nanine de Groot, Marit K. H. van der Wiel, Nel Otting, Annemiek J. M. de Vos-Rouweler, Natasja G. de Groot and Ronald E. Bontrop J Immunol February 28, 2020, ji1901140; DOI: https://doi.org/10.4049/jimmunol.1901140 Key Points KIR genes evolved rapidly in closely related macaque species and their populations. Hybrid KIR genes in macaques are generated frequently by recombination.
Open in Who Shared Issue with article?
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