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Nanying Chen

As seen in: Wiley Online Library
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Articles

Identification of Two Novel HLA-DQB1 Alleles, HLA-DQB1*02:239 and HLA-DQB1*02:271

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By Wenwen Pi, Fang Wang, Nanying Chen
| Wiley Online Library Verified
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are freely available in the IPD-IMGT/HLA Database. References 1, , , et al., “The IPD-IMGT/HLA Database: Recent Developments in Sequence Submission,” Nucleic Acids Research 54 (2026): D1152–D1158. 2, , , et al., “The Polymorphism of HLA-A, -C-B, -DRB3/4/5, -DRB1, -DQB1 Loci in Zhejiang Han Population, China.
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Characterisation of the Novel HLA-DQB1*05:01:56 Allele Using Next-Generation Sequencing in a Chinese Cord Blood Donor

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By Nanying Chen, Fang Wang, Wenwen Pi
| Wiley Online Library Verified
Currently, over 30,894 HLA alleles have been identified in populations around the world, including 3121 alleles for HLA-DQB1 locus according to the latest version of the IPD-IMGT/HLA Database release 3.65 version (July, 2026) [1]. HLA-DQB1*05:01 is a common allele with the frequency of 4.62% in the Chinese Han population [2].
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Characterisation of the Novel HLA-C*06:390 Allele by Next-Generation Sequencing

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By Qi Li, Nanying Chen, Fang Wang
| Wiley Online Library Verified
The HLA system has proven to be the most polymorphic region in the human genome and matching for HLA between the donor and recipient plays an important role in the successful outcome of haematopoietic stem cell transplantation [1, 2]. The HLA-C locus is classical HLA class I genes; the genetic variations in HLA-C locus can determine susceptibility or resistance to certain diseases [3].
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