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Narcisa Ianopol on Muck Rack

Narcisa Ianopol

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Articles

Neuroprotective effect of intraperitoneal Humanin-G in retinal degeneration of Royal College of Surgeons rats

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By Bin Lin, Kevin Schneider, Mustafa Ozgul, Magdalene Seiler, Narcisa Ianopol
| Nature Verified
Abstract This study aimed to examine whether Humanin-G (HNG), a mitochondrial derived peptide with cytoprotective properties, could improve the retinal function and gene expression in Royal College of Surgeons (RCS) rats with retinal pigment epithelium (RPE) dysfunction and retinal degeneration. Starting at postnatal day 21, RCS rats received twice a week intraperitoneal injection of either Low Dose HNG (0.4 mg/kg), High Dose HNG (4 mg/kg), or sham-saline for 1 or 4 weeks.
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