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Narufumi Kitamura

As seen in: Wiley Online Library, MDPI
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Articles

Mitochondrial dynamics as a novel treatment strategy for triple‐negative breast cancer

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By Yuechen Wang, Narufumi Kitamura, Yuto Yamazaki, Narumi Harada-Shoji
| Wiley Online Library Verified
1 INTRODUCTION Breast cancer (BC) is the most frequently diagnosed malignant tumor among women globally and ranks as the second leading cause of mortality.1 Typically, it is classified based on hormone receptor (HR) expression, specifically including estrogen receptor (ER) and progesterone receptor (PR), as well as the presence of human epidermal growth factor receptor 2 (HER2).
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Clinical Significance of ABCG2/BCRP Quantified by Fluorescent Nanoparticles in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

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By Hiroshi Tada, Kohsuke Gonda, Narufumi Kitamura, Takanori Ishida
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Hiroshi Tada 1,*, Kohsuke Gonda 2, Narufumi Kitamura 2 and Takanori Ishida 1 1 Division of Breast and Endocrine Surgical Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Miyagi, Japan 2 Department of Medical Physics, Tohoku University Graduate School of Medicine, Sendai 980-8575, Miyagi, Japan * Author to whom correspondence should be addressed.
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Abstract 5243: Prognostic value of nuclear and non-nuclear estrogen receptor expression by immunohistochemistry with phosphor-integrated dots in hormone receptor-positive early breast cancer

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By Zhaorong Guo, Yoh Hamada, Hiroshi Tada, Narufumi Kitamura
| cancerres.aacrjournals.org
Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, ILAbstractBackground: Estrogen receptor α (ERα) is associated to cell proliferation and survival through genomic (nuclear) and non-genomic (non-nuclear) signaling pathway. Endocrine therapy is the most effective therapies for patients with hormone receptor(HR) positive breast cancer. Recent progress shows that both nuclear and non-nuclear crosstalk was considered to contribute to endocrine resistance.
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