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Articles by Natália Talim
From the ONTT to Antibody-Mediated Optic Neuritis: Four Decades of Progress and Unanswered Question
Submitted: 15 December 2025 You are already at the latest version Optic neuritis (ON) has been recognized since antiquity, but its modern clinical identity emerged only in the late 19th century and was definitively shaped by the Optic Neuritis Treatment Trial (ONTT). The ONTT established the natural history, visual prognosis, association with multiple sclerosis (MS), and therapeutic response to corticosteroids, building the foundation for contemporary ON management.
Prevalence of Neuromyelitis Optica Spectrum Disorder in Belo Horizonte, Southeast Brazil
Highlights • The prevalence rate of neuromyelitis optica spectrum disorders in Belo Horizonte, Brazil is 4.52/100,000 (95% CI 3.72-5.43) • This is the second highest prevalence rate for NMOSD in the world • 87% of patients were female; 64% non-white, and 67% tested positive for serum AQP4-IgG • The high prevalence rate may result from the strong Afro-descent component of the Brazilian population Abstract Background : Studies on the prevalence of neuromyelitis optica spectrum disorder (NMOSD)...
Optic neuritis at disease onset predicts poor visual outcome in neuromyelitis optica spectrum disorders.
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Figure 1 Flowchart of patients in the study. Figure 2 Disability scores of NMOSD patients according to time of optic neuritis occurrence. ON: optic neuritis. EDSS: Expanded disabillty status scale. KVS: Kurtzke's visual function scale. WONIS: Wingerchuk optic nerve impairment scale. Highlights •Patients with NMOSD and optic neuritis have severe sustained disability.
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Publication HistoryPublished online: September 12, 2018Accepted: August 30, 2018; Received: August 29, 2018;
MYELITIS AND CAUDA EQUINA INVOLVEMENT FOLLOWING DENGUE FEVER. A CASE REPORT AND REVIEW OF THE LITERATURE
Publication HistoryPublished online: December 20, 2017Accepted: December 19, 2017; Received in revised form: December 11, 2017; Received: August 10, 2017;
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