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Nayel I. Khan on Muck Rack

Nayel I. Khan

As seen in: Wiley Online Library, Texas Medical Center
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Articles

"p90RSK Pathway Inhibition Synergizes With Cisplatin in TMEM16A Overexp" by Abdulkader Yassin-Kassab, Suman Chatterjee et al.

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By Abdulkader Yassin-Kassab, Suman Chatterjee, Nayel I. Khan, Nathaniel Wang
| Texas Medical Center
Keywords Humans, Antineoplastic Agents, Apoptosis, Cell Line, Tumor, Cisplatin, Drug Resistance, Neoplasm, Head and Neck Neoplasms, Squamous Cell Carcinoma of Head and Neck, Ribosomal Protein S6 Kinases, 90-kDa, Anoctamin-1 Abstract Head and neck squamous cell carcinoma (HNSCC) constitutes one of the most common types of human cancers and often metastasizes to lymph nodes. Platinum-based chemotherapeutic drugs are commonly used for treatment of a wide range of cancers, including HNSCC.
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Subcategorization of Perineural Invasion Stratifies Oral Cavity Squamous Cell Carcinoma Prognosis

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By Nicholas Siu-Kay Fung, Cara M. Fleseriu, Randall J. Harley, Nayel I. Khan
| Wiley Online Library Verified
Objective To evaluate whether subcategorization of perineural invasion (PNI) improves the prognostic resolution of the American Joint Committee on Cancer, Eighth Edition (AJCC8) staging system in oral cavity squamous cell carcinoma (OCSCC). Methods OCSCC tumor specimens from patients seen at a tertiary care institution who underwent primary surgical resection between January 2019 and June 2021 were sorted into four PNI categories: negative, intratumoral, peripheral, and extratumoral.
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