Nazhifah Salim on Muck Rack

Nazhifah Salim

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Articles

NKG7 is a stable marker of cytotoxicity across immune contexts and within the tumor microenvironment

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By Roberta Turiello, Susanna Ng, Elisabeth Tan, Nazhifah Salim
| biorxiv.org
Abstract Cytotoxicity is a cornerstone of immune defense, critical for combating tumors and infections. This process relies on the coordinated action of granzymes and pore-forming proteins, with Granzyme B (GZMB) and Perforin (PRF1) being key markers and the most widely studied molecules pertaining to cytotoxicity. However, other human granzymes and cytotoxic components remain underexplored, despite growing evidence of their distinct, context-dependent roles.
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