Nazmiye Arslan

Abstract Gene expression is regulated at the transcriptional and translational levels and a plethora of epigenetic mechanisms. Regulation of gene expression by transposable elements is well documented. However, a comprehensive analysis of their regulatory roles is challenging due to the lack of dedicated approaches to define their contribution. Here, we present regulaTER, a new R library dedicated to deciphering the regulatory potential of transposable elements in given phenotype.

Abstract Gene expression defines the identity of cells and is achieved following multiple levels of regulation at the transcriptional, translational, and a plethora of profound epigenetic mechanisms. Regulation of gene expression by transposable elements (TEs) is well documented. However, comprehensive analysis of the regulatory role of TEs is challenging due to the lack of dedicated analysis approaches to define their contribution.