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Perceived Neighborhood Disadvantage Predicts Similarity in Amygdala Representations of Negative and Neutral Images in Early Adolescents
1 Introduction Adolescence is a critical developmental period characterized by rapid brain maturation and heightened neural plasticity (Blakemore et al. 2010; Grayson and Fair 2017; Sisk and Foster 2004). During this developmental phase, environmental factors are especially likely to influence brain development (Hertzman and Boyce 2010; Nelson and Gabard-Durnam 2020).
Hospital Capacity Pooling in Pandemics: Simulation-Based Mortality Impacts and Diversification Mechanisms
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data and code supporting this article are available in Zenodo at https://doi.org/10.5281/zenodo.21500085 Supporting Information Filename Description risa70329-supp-0001-SuppMat.docx4 MB Supporting Figure S1. Predicted maximum ICU occupancy of regression models shown for the full range of service populations included in the model (A,B).
People‐Centered Approaches That Can Expand the Role of Evaluator
1 Introduction This article tells the collaboratively developed story of a group of seasoned external evaluators who utilized people-centered approaches as part of their role leading a collective impact initiative. People-centered evaluation is a relational and reflexive approach to evaluation that is fostered and sustained by respect and reciprocity between evaluators and the communities we strive to serve (Bledsoe and Pérez-Troncoso 2025).
Implementation context of outpatient physical therapy clinics preparing to launch a new evidence-based clinical program for knee osteoarthritis: Findings from a national multisite implementation trial
Keywords Osteoarthritis of the Knee Implementation Science Physical therapy department Physical Medicine and Rehabilitation Outpatient Health Services Veterans List of abbreviations (BRT) (Benchmark Resilience Tool) (ADAPT) (Durham VA Center to Accelerate Discovery and Practice Transformation) (EBP) (Evidence based practice) (Group PT) (Group Physical Therapy for Veterans with knee OA) (ICS) (Implementation Climate Scale) (OA) (Knee osteoarthritis) (ORIC) (Organizational Readiness for...
Effects of Bacillus subtilis ATCC PTA-122264 on Apparent Total Tract Macronutrient Digestibility and Fecal Characteristics, Metabolites, and Microbiota of Healthy Adult Dogs
Gastrointestinal and stool quality issues are common in companion animals. In addition to dietary fibers and prebiotics, the consumption of live microorganisms may be used to support the gastrointestinal health of pets. Spore-forming Bacillus species are gaining interest due to their viability during processing, storage, and within the gastrointestinal tract. The objective of the current study was to determine the effects of B.
Utilization of the QuPath open-source software platform for analysis of mammalian spermatogenesis
The adult mammalian testis is filled with seminiferous tubules, which contain somatic Sertoli cells along with germ cells undergoing all phases of spermatogenesis. During spermatogenesis in postnatal mice, male germ cells undergo at least 17 different nomenclature changes as they proceed through mitosis as spermatogonia (=8), meiosis as spermatocytes (=6), and spermiogenesis as spermatids (=3) [1–6].
International Business Times
Hotel Liquidation Store Inc. is a leading hotel liquidation and furniture removal company with nearly a decade of experience. Burlington, NC USA - November 1, 2024 — Hotel Liquidation Store Inc., a premier hotel liquidation company known for its expert furniture removal services in the hospitality sector, is excited to announce a new Florida home office. The office is scheduled to open on November 12, 2024. This expansion will position Hotel Liquidation Store Inc.
Irreversible Inhibition of DNMT3A by an N‐Mustard Analog of S‐Adenosyl‐L–Methionine
Introduction DNA methylation plays an integral role in epigenetics across all kingdoms of life from bacteria to mammals.
Overcoming Challenges to Research Success in Cardiothoracic Anesthesiology Fellowship Training
1 Rankings of Medical Schools and Their Departments. It is a challenging time for cardiothoracic anesthesiologists to succeed as clinical researchers.
Mariner: Explore the Hi-Cs
3D chromatin structure plays an important role in regulating gene expression and alterations to this structure can result in developmental abnormalities and disease. While genomic approaches like Hi-C and Micro-C can provide valuable insights in 3D chromatin architecture, the resulting data sets are extremely large and difficult to manipulate. Here, we present mariner, a rapid and memory efficient tool to extract, aggregate, and plot data from Hi-C matrices within the R/Bioconductor environment.
Admix-kit: an integrated toolkit and pipeline for genetic analyses of admixed populations
Admixed populations, with their unique and diverse genetic backgrounds, are often underrepresented in genetic studies. This oversight not only limits our understanding but also exacerbates existing health disparities. One major barrier has been the lack of efficient tools tailored for the special challenges of genetic study of admixed populations. Here, we present admix-kit, an integrated toolkit and pipeline for genetic analyses of admixed populations.
Cannot obtain surround sound of any kind from Roku Ultra
#1 Hello all! New to this forum, but old with AV. I am having an issue I cannot figure out. Not sure if it should go here or in the AVR forum, so I'll try here since all signs to me point to the Roku. I have a Roku Ultra connected via HDMI to a NAD 757V3 which connects to my TV with HDMI. In addition I have a computer connected to the AVR with HDMI and Analog (for reasons), plus a BluRay player using HDMI and a DVD/SACD player using optical.
ExEmPLAR (Extracting, Exploring and EMbedding Pathways Leading to Actionable Research): A User-friendly Interface for Knowledge Graph Mining
Knowledge graphs are being increasingly used in biomedical research to link large amounts of heterogenous data and facilitate reasoning across diverse knowledge sources. Wider adoption and exploration of knowledge graphs in the biomedical research community is limited by requirements to understand the underlying graph structure in terms of entity types and relationships, represented as nodes and edges, respectively, and learn specialized query languages for graph mining and exploration.
Is It Time to Stop Living in a HeartMate II World?
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The importance of quality data to track global progress in addressing stillbirths and neonatal mortality
About 2·4 million neonatal deaths1 and 2·0 million stillbirths2 occur each year globally, with 98% of these deaths occurring in low-income and middle-income countries (LMICs). Accurate counting of stillbirth and neonatal deaths is crucial to understanding the true burden of mortality and necessary to understanding countries' progress towards meeting national and international health goals, such as the UN Sustainable Development Goals (SDGs).
Parahydrogen‐Induced Carbon‐13 Radiofrequency Amplification by Stimulated Emission of Radiation
Graphical Abstract Carbon-13 Radiofrequency Amplification by Stimulated Emission of Radiation (C-13 RASER) is demonstrated on a bolus of liquid hyperpolarized ethyl [1-13C]acetate. Spontaneous RASER signal emissions were detected using a non-cryogenic 1.4T NMR spectrometer equipped with a radio-frequency detection coil with a quality factor of 32 without any modifications for over 3 minutes, paving the way to new frontiers for HP 13C contrast agents.
Creating Inclusive Learning Environments for Chinese and American Pediatric Nursing Students
Students participated synchronously in the virtual simulation. At the conclusion of the debrief, students were asked to reflect on their overall experience discuss their perceptions on their participation in the simulation and its influence on their thoughts regarding DEI concepts. Some students volunteered to share their self-reflections verbally with the entire group, and others elected to write their self-reflections.
School Masking Policies and Secondary SARS-CoV-2 Transmission
Citation Angelique E. Boutzoukas, Kanecia O. Zimmerman, Moira Inkelas, M. Alan Brookhart, Daniel K. Benjamin, Sr., Sabrina Butteris, Shawn Koval, Gregory P. DeMuri, Vladimir G. Manuel, Michael J. Smith, Kathleen A. McGann, Ibukunoluwa C. Kalu, David J. Weber, Amy Falk, Andi L. Shane, Jennifer E. Schuster, Jennifer L. Goldman, Jesse Hickerson, Vroselyn Benjamin, Laura Edwards, Tyler R. Erickson, Daniel K. Benjamin, Jr.; School Masking Policies and Secondary SARS-CoV-2 Transmission.
Quarantine Elimination for K-12 Students With Mask-on-Mask Exposure to SARS-CoV-2
Skip Nav Destination Article navigation Research Article| November 04 2021
Building a National Framework to Pair Scientists and Schools During a Global Pandemic
Skip Nav Destination Article navigation Pre-publication Release| November 04 2021
School Safety, Masking, and the Delta Variant
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Reinventing Food Banks & Pantries: Tools to End Hunger. Katie S. Martin. 2021. Washington, DC: Island Press, 288 pages, ISBN: 9781642831535, paperback. - Mercer - 2021 - Culture, Agriculture, Food and Environment - Wiley Online Library
Book Review Shanara Mercer, University of North Carolina, Charlotte, NC, USA Search for more papers by this author Claire Patrick, University of North Carolina, Charlotte, NC, USA Search for more papers by this author Nicole D. Peterson, PDF ShareShare Get access to the full version of this article. View access options below. Institutional Login Loading institution options... Log in to Wiley Online Library If you have previously obtained access with your personal account, please log in.
Strain-dependent inhibition of Clostridioides difficile by commensal Clostridia encoding the bile acid inducible (bai) operon
Research Article A.D. Reed, M.A. Nethery, A. Stewart, R. Barrangou, C.M. Theriot DOI: 10.1128/JB.00039-20 ABSTRACT Clostridioides difficile is one of the leading causes of antibiotic-associated diarrhea. Gut microbiota-derived secondary bile acids and commensal Clostridia that encode the bile acid inducible (bai) operon are associated with protection from C. difficile infection (CDI), although the mechanism is not known.
High‐ and low‐dose oral immunotherapy similarly suppress pro‐allergic cytokines and basophil activation in young children
1 INTRODUCTION Oral immunotherapy (OIT) has been used in research settings for the past decade and is now being evaluated in a Phase III clinical trial in subjects with peanut allergy.
Parallel community solutions for cardiovascular risk reduction
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Tree nut allergies: Allergen homology, cross‐reactivity, and implications for therapy
Tree nut allergy is a potentially life‐threatening disease that is increasing in prevalence, now affecting 1% of the general population in the United States. While other food allergies often resolve spontaneously, tree nut allergies are outgrown in less than 10% of cases. Due to the likelihood of cross‐sensitization to multiple tree nut allergens, the current treatment guideline is strict avoidance of all nuts once one tree nut allergy has been diagnosed.
Enhanced heroin self-administration and distinct dopamine adaptations in female rats
Journal List Neuropsychopharmacology v.46(10); 2021 Sep PMC8358024 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more about our disclaimer. Brianna E. George 1Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC USA Samuel H.
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
Journal List Nat Commun PMC6954302 Timothy P. Sheahan 1Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC USA Amy C. Sims 1Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC USA Sarah R.
Six Persistent Research Misconceptions
A surprising number of misconceptions persist in the conduct of research involving human subjects. Some persist despite teachings to the contrary, and some because of teachings that should be to the contrary. To spark discussion of these issues, I list here six persistent research misconceptions, and offer a capsule summary of the problems with each of them. Misconception 1.
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