Neetesh Pandey on Muck Rack

Neetesh Pandey

As seen in: Alzheimer's Research and Therapy, BioRxiv
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Articles

Plasma phospho-tau217 as a predictive biomarker for Alzheimer’s disease in a large south American cohort - Alzheimer's Research & Therapy

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By Neetesh Pandey, Zikun Yang, Basilio Cieza, Dolly Reyes-Dumeyer, Rosa Montesinos, Marcio Soto-Añari, Nilton Custodio, Lawrence S. Honig, Giuseppe Tosto
| Alzheimer's Research and Therapy
We included Peruvians from the Genetic of Alzheimer Disease in Peruvian Populations (GAPP) study. This cross-sectional case-control study was initiated in 2020 aiming to include mestizos from Lima and indigenous groups from Southern cities of Arequipa and Puno (Aymaras and Quechuas individuals) to study the effect of ancestry on AD.
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Deciphering drug response and phenotypic heterogeneity of cancer cells using gene ensembles of regulatory units defined by chromatin domains

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By Neetesh Pandey, Madhu Sharma, Arpit Mathur, George Anene Nzelu
| BioRxiv
Abstract The effect of co-localization of genes in the topologically associated domains (TADs) and their activity as a regulatory unit in cancer samples and cells, together with drug-response, needs comprehensive analysis. Here, we analyzed the activity of TADs using cancer-cell transcriptomes along with chromatin-interaction and epigenome profiles to understand their relationship with drug-response.
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Deciphering the phenotypic heterogeneity and drug response in cancer cells using genome-wide activity and interaction of chromatin domains.

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By Neetesh Pandey, Madhu Sharma, Arpit Mathur, George Anene Nzelu
| BioRxiv
Abstract The effect of colocalization of genes in the topologically associated domains (TADs) and their activity orchestration in cancer samples and cells, hand-in-hand with drug-response have not been comprehensively studied. Here, we analyzed patterns in the activity of TADs in cancer-cells along with chromatin interaction profiles to understand their modes of drug-response.
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