Neil Tay

Abstract CRISPR-based genetic perturbation screens have revolutionized the ability to link genes to cellular phenotypes with unprecedented precision and scale; however, conventional pooled CRISPR screens require large cell numbers to achieve adequate sgRNA representation, posing technical and financial challenges.

New technologies are providing researchers with incredible opportunities to dig deeper into the mysteries of cancer biology and devise creative approaches to combat this pervasive disease. Each year, thousands of researchers from across the world gather at the American Association for Cancer Research (AACR) Annual Meeting to share groundbreaking scientific advances, including exciting new tools to study and treat cancer.

Influenza and asthma are two of the major public health concerns in the world today. During the 2009 influenza pandemic asthma was found to be the commonest comorbid illness of patients admitted to hospital. Unexpectedly, it was also observed that asthmatic patients admitted to hospital with influenza infection were less likely to die or require admission to intensive care compared with non-asthmatics.