Neissa Usanase

The quinazolinone scaffold, which consists of fused benzene and pyrimidinone rings, is found in compounds with wide-ranging biological properties, including anticancer, anti-inflammatory, and antimicrobial activities (Figure 1). (1) Among the structurally diverse quinazolinone derivatives, quinazolin-4(3H)-ones have emerged as privileged structures in drug discovery, prompting the development of innovative synthetic strategies for their preparation and evaluation of their medicinal potential.