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Nela Pragathi Sneha on Muck Rack

Nela Pragathi Sneha

As seen in: MDPI
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Articles

Tracing ALS Degeneration: Insights from Spinal Cord and Cortex Transcriptomes

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By Nela Pragathi Sneha, Y.-H. Taguchi, M. Michael Gromiha, Nela Pragathi
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Investigating Neuron Degeneration in Huntington’s Disease Using RNA-Seq Based Transcriptome Study

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By Y.-H. Taguchi, Nela Pragathi Sneha, M. Michael Gromiha, Nela Pragathi
| MDPI
1. Introduction Huntington’s disease (HD) is a trinucleotide repeat disorder caused by a CAG repeat expansion affecting the medium spiny neurons in the brain [1,2,3,4]. CAG repeat expansion is caused by the HTT gene, which encodes for the huntingtin protein [5,6,7]. HD is a serious neurodegenerative disorder with motor and cognitive symptoms such as chorea and memory loss, respectively.
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