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Introduction Hereditary sensory neuropathy type 1 (HSN1) is one of the most common sensory neuropathies displaying a progressive loss of pain and temperature sensation in the distal limbs, with distal and later proximal limb weakness (Nicholson, 2002; Houlden et al., 2004, 2005). Owing to loss of sensation, painless injuries develop, often complicated by ulcerations and osteomyelitis, eventually requiring amputation (Nicholson, 2002).
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